January 5, 2022

A monthly recap of the latest news about Alzheimer’s and dementia

Viagra associated with reduced risk of Alzheimer’s disease

People who took the drug sildenafil were less likely to develop Alzheimer’s disease. In cultured human neurons, sildenafil enhanced growth and reduced Alzheimer’s biomarkers. The findings support further investigation of sildenafil as a possible treatment for Alzheimer’s disease. Read more here.

Researchers map glycosylation patterns associated with Alzheimer’s disease

Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer’s disease. Read more here.

Repurposed cancer treatments could be potential Alzheimer’s drugs

A data-driven analysis method aimed at speeding up testing of potential Alzheimer’s disease therapies identified two existing cancer drugs, one FDA-approved and another still experimental, as having promise for being repurposed for Alzheimer’s disease. Read more here.

Data shows racial disparities in Alzheimer’s disease diagnosis between Black and white research study participants

Black participants in Alzheimer’s disease research studies were 35% less likely to be diagnosed with Alzheimer’s and related dementias than white participants, despite national statistics that indicate that Black Americans are overall about twice as likely to develop dementias than whites. Read more here.