A monthly recap of the latest news about Alzheimer’s and dementia

New blood test can detect ‘toxic’ protein years before Alzheimer’s symptoms emerge, study shows

A team led by researchers at the University of Washington has developed a laboratory test that can measure levels of amyloid beta oligomers in blood samples. Read more here.

 

Alzheimer’s tied to cholesterol, abnormal nerve insulation

Researchers found evidence that the Alzheimer’s-related gene APOE4 disrupts cholesterol management in the brain and weakens insulation around nerve fibers. Read more here.

 

An experimental Alzheimer’s drug could be approved next year. But it comes with risks

Researchers say the experimental Alzheimer’s drug Lecanemab represents an important advance and is likely to get FDA approval in 2023, despite some safety concerns. Read more here.

 

Swelling Along Brain’s Axons May Be True Culprit in Alzheimer’s Disease

Yale researchers have found, that swelling caused by a byproduct of amyloid plaques may be the true cause of the disease’s debilitating symptoms. Read more here.

 

Alzheimer’s progression in Down syndrome appears similar to other genetic, early onset forms of the disease

NIH-funded study suggests people with Down syndrome may benefit from Alzheimer’s disease treatments. Read more here. 

 

Exploring sensory decline and dementia risk

About one third of older adults have some form of vision problems or loss by age 65, and nearly 50% of people older than 75 have disabling hearing loss. Read more here.