A monthly recap of the latest news about Alzheimer’s and dementia

Artificial Intelligence Approach May Help Detect Alzheimer’s Disease from Routine Brain Imaging Tests

Researchers have developed and validated a deep learning–based method to detect Alzheimer’s disease based on routinely collected clinical brain images. Read more here.


Yale study sheds light on why women might be more prone to Alzheimer’s

Key structural differences in the brain region responsible for wakeful rest may explain women’s higher risk of developing Alzheimer’s disease. Read more here.


Alzheimer’s Study Links Cholesterol And Toxic Protein Clusters

A study from Texas A&M’s Department of Biochemistry and Biophysics more closely connects diet and Alzheimer’s disease development. Read more here. 


FDA will review Eisai and Biogen’s Alzheimer’s treatment Leqembi with decision on full approval expected in early July

Leqembi slowed disease progression by 27% in clinical trials, but it carries risks of brain swelling and bleeding. The FDA will make a decision on full approval of Eisai’s early Alzheimer’s disease treatment Leqembi in July. Read more here.


Mediterranean and MIND diets reduced signs of Alzheimer’s in brain tissue, study finds

People who consumed foods from the plant-based Mediterranean and brain-focused MIND diets had fewer of the hallmark signs of Alzheimer’s — sticky beta-amyloid plaques and tau tangles in the brain — when autopsied, a new study found. Read more here.


Hydroxychloroquine lowers dementia risk in humans, improves molecular signs of Alzheimer’s in mouse and cell models

Taking hydroxychloroquine (HCQ) is linked to lower rates of Alzheimer’s disease and related dementias in people with rheumatoid arthritis, according to an international team of researchers led by NIA scientists. Read more here.


Alzheimer’s may increase DNA variants in brain neurons

The findings from this NIA-funded study, published in Nature, suggest a link between genomic damage to neurons and the development of pathological hallmarks of Alzheimer’s. Read more here.